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New Study Criticizes Research Methodologies Assessing PFAs Risks



Center for Truth in Science New scientific review finds insufficient data to draw accurate conclusions about the association of PFAS with any specific disease

A new critical review of existing research on per- and polyfluoroalkyl substances (PFAS) found that most PFAS studies to-date include insufficient data to draw accurate conclusions about the association of PFAS with any specific disease. A central recommendation from the authors is the need for additional specific research to properly calculate human-relevant dose to further link associations with human risk assessment and help set tolerable daily intake.


The critical review is featured in the latest issue of Environmental Research, a peer-reviewed environmental science and environmental health journal, and was performed by the Center of Environmental Food and Toxicological Technology at the University of Rovira i Virgili in Spain. This is the first review where highly referred articles on PFAS used for policymaking by several regulatory agencies were collected and evaluated based on the review guidelines developed by the U.S. National Toxicology Program’s Office of Health Assessment and Translation review guidelines. This new critical review provides key insight for improving methodological protocols for future PFAS experimental studies. The review was performed in accordance with PRISMA guidelines, the most rigorous set of internationally accepted criteria guiding the reporting of systematic reviews and meta-analyses.


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